Medicines That Affect Vitamin B12 Absorption Identified by Apollo Neurologist
The warning about medicines that affect vitamin B12 absorption has gained attention after a recent explanation by Dr. Sudhir Kumar, a senior neurologist at Apollo Hospitals, Hyderabad. In his educational video, Dr. Kumar highlighted how two widely prescribed types of medication metformin and proton pump inhibitors (PPIs) can gradually reduce the body’s ability to absorb vitamin B12, leading to potential deficiency over time..jpg)
Vitamin B12 is essential for nerve function, red blood cell production, and mental clarity. A deficiency can cause fatigue, weakness, tingling sensations, and even memory or mood issues. While diet is often blamed for low B12 levels, Dr. Kumar emphasized that the hidden cause in many cases could be long-term medication use.
How These Medicines That Affect Vitamin B12 Interfere With the Body
Among the medicines that affect vitamin B12, metformin is one of the most common. It is widely prescribed to people with diabetes, and sometimes for polycystic ovary syndrome (PCOS) and metabolic conditions. Dr. Kumar explained that metformin interferes with vitamin B12 absorption in the small intestine. When used over several years, it can lead to a slow but steady reduction in the body’s B12 reserves.
He advised that patients who have been taking metformin for a long time should undergo routine B12 testing every one to two years. Early symptoms such as tiredness, numbness, and forgetfulness should not be ignored, as they may indicate low B12 levels.
The second major category of medicines that affect vitamin B12 includes proton pump inhibitors (PPIs). These drugs, such as omeprazole, pantoprazole, rabeprazole, and esomeprazole, are commonly used for acidity, reflux, and peptic ulcers. PPIs reduce stomach acid which is necessary to extract vitamin B12 from food thereby decreasing its absorption when taken for extended periods.
Dr. Kumar noted that people who rely on PPIs for chronic digestive issues might unknowingly become deficient in vitamin B12. Since stomach acid plays a vital role in breaking down food and releasing nutrients, reduced acid levels can significantly impact B12 availability in the body.
Preventing Deficiency Caused by Medicines That Affect Vitamin B12
Dr. Kumar clarified that individuals should not discontinue metformin or PPIs without medical advice, as these medications serve important roles in managing chronic conditions. Instead, he recommended a preventive approach involving regular vitamin B12 level monitoring, early detection, and supplementation when necessary.
Those experiencing early signs of deficiency such as weakness, mood swings, tingling in hands or feet, and poor concentration should get tested promptly. If deficiency is confirmed, B12 supplements or dietary adjustments can help restore normal levels.
He also suggested that doctors could consider periodic vitamin supplementation for long-term users of these drugs, particularly elderly patients, who are more likely to face absorption difficulties.
Why Awareness of Medicines That Affect Vitamin B12 Matters
Dr. Kumar’s message highlights a crucial but often overlooked aspect of preventive healthcare understanding the side effects of long-term medication use. Many people depend on these drugs for years without realizing that they might be compromising their nutritional balance.
Raising awareness about medicines that affect vitamin B12 can help individuals take timely action before symptoms become severe. Regular health checkups, along with responsible medication management, can prevent deficiencies and related complications such as nerve damage or cognitive decline. Also Read: Tamil Nadu Insists on Rs. 15,000 Crore Foxconn Deal: Truth Behind the Controversy Unfolds
Conclusion
The warning about medicines that affect vitamin B12 serves as a reminder that even commonly prescribed drugs can influence vital nutrients in subtle ways. Long-term users of metformin and PPIs should remain alert, undergo routine B12 checks, and consult their doctors for preventive supplementation. With simple monitoring and timely care, the risks can be managed effectively, ensuring both medication benefits and overall health remain balanced.
